Compare · 2 funds side by side · dividends reinvested

IBRN and XBI

IBRNiShares×XBISPDR×

Versus in desk

Story of the two · Growth5Y$10,000 five years agoDividends reinvested · both on one scale$12,576XBI · best of the two

02 / 04

IBRN and XBI, Ranked

Today

FundFeeYieldYTD1 year3 yrs · yr5 yrs · yrWorst dropVolatilityAssetsAvg rank

State Street SPDR S&P Biotech ETFSectors · Health care0.35%0.35%+27.2%+38.1%+34.5%+4.7%−14.9%29.1%$10.5B1.3

iShares Neuroscience and Healthcare ETFSectors · Health care0.47%0.96%+3.0%+11.3%+21.0%[…]−26.3%26.7%$7M1.7

Rank among the two1st → 2ndFee, drop and volatility: lower ranks higherAvg rank: mean of the 8 ranks · 1 is best

End-of-day Nov 3, 2026 · returns include dividends · since: IBRN 2022 · XBI 2006

Head to Head

Swap sides Versus in desk

Head to Head

iShares Neuroscience and Healthcare ETF · $7M[…]

IBRN

XBI

State Street SPDR S&P Biotech ETF · $10.5B$12,576

$10,000 five years ago, dividends reinvested · they hold 12.4% in common

IBRNMeasureXBI

+3.0%Year to dateJan 1 → Nov 3+27.2%

+11.3%1 yearTotal return+38.1%

+21.0%3 years · per year$10,000 became $17,703 · $24,320+34.5%

[…]5 years · per year$10,000 became […] · $12,576+4.7%

0.47%Expense ratio$47 · $35 a year on $10k · lower is better0.35%

0.96%Trailing 12-mo yield$96 · $35 a year on $10k0.35%

−26.3%Worst dropSmaller is better−14.9%

26.7%VolatilityLower is calmer29.1%

IBRNXBI Winner of the row, in its colourEach row: the bigger of the two fills its side

2–5XBI wins

End-of-day Nov 3, 2026 · returns include dividends · 3Y and 5Y figures are per-year returns

More Ways to See the Pairs

IBRN vs XBI: Top 5 Holdings

Today

IBRN

23.5%in top 5

XBI

in top 59.7%

IBRNStockXBI

5.6%BIIB1.7%

4.8%ALKSnot top 5

4.6%NBIXnot top 5

4.4%EWTXnot top 5

4.2%PTCTnot top 5

not top 5MRNA2.4%

not top 5TWST2.0%

not top 5NTRA1.9%

not top 5HALO1.8%

Held in common12.4%

End-of-day Nov 3, 2026 · share of each fund

IBRN vs XBI Returns, Every Period

iSharesIBRN

+11.3%

past year

XBISPDR

+38.1%

past year

IBRNXBIFaded: behind in that period

0–3XBI wins

End-of-day Nov 3, 2026 · dividends in · faded = behind in that period

IBRN vs XBI

YTD

iSharesIBRN

+3.0%

XBISPDR

+27.2%

+3.0%Year to date+27.2%

−26.3%Worst drop · 1Y−14.9%

26.7%Volatility · 1Y29.1%

1.0%Yield0.4%

$6.6MAssets$10.5B

2–2level

End-of-day Nov 3, 2026 · smaller drop and lower volatility win

Cost, Income and Risk

Fees: IBRN, XBI

Today

0.35%lowest, XBI

FundExpense ratioFee$10k

XBI0.35%$35

IBRN0.47%$47

End-of-day Nov 3, 2026 · fee on $10,000 a year

Yields: IBRN, XBI

0.96%highest, IBRN

FundTrailing yieldYield$10k

IBRN0.96%$96

XBI0.35%$35

End-of-day Nov 3, 2026 · trailing 12-month yield

Income After Fees on $10,000

$49most kept, IBRN

IBRN$96 − $47 = $49

XBI$35 − $35 = $0

KeptFee

End-of-day Nov 3, 2026 · yield in dollars minus the fee

Overlap: IBRN, XBI

Today

12.4%most shared, IBRN and XBI

IBRNXBI

IBRN—12.4%

XBI12.4%—

End-of-day Nov 3, 2026 · share held in common · outlined: the pair in versus

Return vs Bumpiness: 2 ETFs

+38.1%XBI, at 29.1% volatility

IBRNWorst drop−26.3%26.7% vol

XBIWorst drop−14.9%29.1% vol

End-of-day Nov 3, 2026 · up and left is better

Paid More vs Made More

YTD

IBRNXBI

+3.0%Year to date+27.2%

1.0%Yield0.4%

+11.3%Past year+38.1%

0.47%Fee0.35%

3–1XBI wins

End-of-day Nov 3, 2026

Popular Pairs Near These Two

SCHD vs VIG

YTD

SchwabSCHD

+32.8%

VIGVanguard

+14.0%

+32.8%Year to date+14.0%

3.0%Yield1.5%

$121BAssets$109B

2–0SCHD wins

End-of-day Nov 3, 2026

JEPQ vs JEPI

YTD

J.P. MorganJEPQ

+7.5%

JEPIJ.P. Morgan

+7.0%

+7.5%Year to date+7.0%

12.3%Yield8.0%

$41.8BAssets$46.0B

2–0JEPQ wins

End-of-day Nov 3, 2026

SPYM vs SPY

YTD

SPDRSPYM

+11.5%

SPYSPDR

+11.5%

+11.5%Year to date+11.5%

1.0%Yield1.0%

$185BAssets$798B

0–0level

End-of-day Nov 3, 2026