Compare · 2 funds side by side · dividends reinvested

TDNA and XBI

TDNAT. Rowe Price×XBISPDR×

Versus in desk

Story of the two · Growth5Y$10,000 five years agoDividends reinvested · both on one scale$12,576XBI · best of the two

02 / 03

TDNA and XBI, Ranked

Today

FundFeeYieldYTD1 year3 yrs · yr5 yrs · yrWorst dropVolatilityAssetsAvg rank

State Street SPDR S&P Biotech ETFSectors · Health care0.35%0.35%+27.2%+38.1%+34.5%+4.7%−14.9%29.1%$10.5B1.0

T. Rowe Price Biotech ETFSectors · Health care0.55%0.00%[…][…][…][…][…][…]$11M2.0

Rank among the two1st → 2ndFee, drop and volatility: lower ranks higherAvg rank: mean of the 8 ranks · 1 is best

End-of-day Nov 3, 2026 · returns include dividends · since: TDNA 2026 · XBI 2006

Head to Head

Swap sides Versus in desk

Head to Head

T. Rowe Price Biotech ETF · $11M[…]

TDNA

XBI

State Street SPDR S&P Biotech ETF · $10.5B$12,576

$10,000 five years ago, dividends reinvested · they hold 58.3% in common

TDNAMeasureXBI

[…]Year to dateJan 1 → Nov 3+27.2%

[…]1 yearTotal return+38.1%

[…]3 years · per year$10,000 became […] · $24,320+34.5%

[…]5 years · per year$10,000 became […] · $12,576+4.7%

0.55%Expense ratio$55 · $35 a year on $10k · lower is better0.35%

0.00%Trailing 12-mo yield$0 · $35 a year on $10k0.35%

[…]Worst dropSmaller is better−14.9%

[…]VolatilityLower is calmer29.1%

TDNAXBI Winner of the row, in its colourEach row: the bigger of the two fills its side

0–2XBI wins

End-of-day Nov 3, 2026 · returns include dividends · 3Y and 5Y figures are per-year returns

More Ways to See the Pairs

TDNA vs XBI: Top 5 Holdings

Today

TDNA

17.7%in top 5

XBI

in top 59.7%

TDNAStockXBI

5.1%ARGXnot top 5

4.8%KYMRnot top 5

2.8%KODnot top 5

2.6%INSMnot top 5

2.5%UTHRnot top 5

not top 5MRNA2.4%

not top 5TWST2.0%

not top 5NTRA1.9%

not top 5HALO1.8%

not top 5BIIB1.7%

Held in common58.3%

End-of-day Nov 3, 2026 · share of each fund

TDNA vs XBI Returns, Every Period

T. Rowe PriceTDNA

[…]

past year

XBISPDR

+38.1%

past year

Returns […]

TDNAXBIFaded: behind in that period

0–0Level

End-of-day Nov 3, 2026 · dividends in · faded = behind in that period

TDNA vs XBI

YTD

T. Rowe PriceTDNA

[…]

XBISPDR

+27.2%

[…]Year to date+27.2%

[…]Worst drop · 1Y−14.9%

[…]Volatility · 1Y29.1%

0.0%Yield0.4%

$11.0MAssets$10.5B

1–0XBI wins

End-of-day Nov 3, 2026 · smaller drop and lower volatility win

Cost, Income and Risk

Fees: TDNA, XBI

Today

0.35%lowest, XBI

FundExpense ratioFee$10k

XBI0.35%$35

TDNA0.55%$55

End-of-day Nov 3, 2026 · fee on $10,000 a year

Yields: TDNA, XBI

0.35%highest, XBI

FundTrailing yieldYield$10k

XBI0.35%$35

TDNA0.00%$0

End-of-day Nov 3, 2026 · trailing 12-month yield

Income After Fees on $10,000

$0most kept, XBI

XBI$35 − $35 = $0

TDNA$0 − $55 = −$55

KeptFee

End-of-day Nov 3, 2026 · yield in dollars minus the fee

Overlap: TDNA, XBI

Today

58.3%most shared, TDNA and XBI

TDNAXBI

TDNA—58.3%

XBI58.3%—

End-of-day Nov 3, 2026 · share held in common · outlined: the pair in versus

Return vs Bumpiness: 2 ETFs

+38.1%XBI, at 29.1% volatility

XBIWorst drop−14.9%29.1% vol

TDNAWorst drop[…][…]

End-of-day Nov 3, 2026 · up and left is better

Popular Pairs Near These Two

SCHD vs VIG

YTD

SchwabSCHD

+32.8%

VIGVanguard

+14.0%

+32.8%Year to date+14.0%

3.0%Yield1.5%

$121BAssets$109B

2–0SCHD wins

End-of-day Nov 3, 2026

JEPQ vs JEPI

YTD

J.P. MorganJEPQ

+7.5%

JEPIJ.P. Morgan

+7.0%

+7.5%Year to date+7.0%

12.3%Yield8.0%

$41.8BAssets$46.0B

2–0JEPQ wins

End-of-day Nov 3, 2026

SPYM vs SPY

YTD

SPDRSPYM

+11.5%

SPYSPDR

+11.5%

+11.5%Year to date+11.5%

1.0%Yield1.0%

$185BAssets$798B

0–0level

End-of-day Nov 3, 2026