Compare · 2 funds side by side · dividends reinvested

XBI and MDEV

XBISPDR×MDEVFirst Trust×

Versus in desk

Story of the two · Growth5Y$10,000 five years agoDividends reinvested · both on one scale$12,272XBI · best of the two

02 / 04

XBI and MDEV, Ranked

Today

FundFeeYieldYTD1 year3 yrs · yr5 yrs · yrWorst dropVolatilityAssetsAvg rank

State Street SPDR S&P Biotech ETFSectors · Health care0.35%0.36%+25.0%+40.0%+31.3%+4.2%−14.9%30.0%$10.9B1.1

First Trust Indxx Medical Devices ETFSectors · Health care0.70%0.10%+7.9%+11.0%+9.0%−2.4%−18.2%17.4%$4M1.9

Rank among the two1st → 2ndFee, drop and volatility: lower ranks higherAvg rank: mean of the 8 ranks · 1 is best

End-of-day Nov 6, 2026 · returns include dividends · since: XBI 2006 · MDEV 2021

Head to Head

Swap sides Versus in desk

Head to Head

State Street SPDR S&P Biotech ETF · $10.9B$12,272

XBI

MDEV

First Trust Indxx Medical Devices ETF · $4M$8,839

$10,000 five years ago, dividends reinvested · they hold 0.0% in common

XBIMeasureMDEV

+25.0%Year to dateJan 1 → Nov 6+7.9%

+40.0%1 yearTotal return+11.0%

+31.3%3 years · per year$10,000 became $22,660 · $12,957+9.0%

+4.2%5 years · per year$10,000 became $12,272 · $8,839−2.4%

0.35%Expense ratio$35 · $70 a year on $10k · lower is better0.70%

0.36%Trailing 12-mo yield$36 · $10 a year on $10k0.10%

−14.9%Worst dropSmaller is better−18.2%

30.0%VolatilityLower is calmer17.4%

XBIMDEV Winner of the row, in its colourEach row: the bigger of the two fills its side

7–1XBI wins

End-of-day Nov 6, 2026 · returns include dividends · 3Y and 5Y figures are per-year returns

More Ways to See the Pairs

XBI vs MDEV: Top 5 Holdings

Today

XBI

9.8%in top 5

MDEV

in top 511.4%

XBIStockMDEV

2.7%MRNAnot top 5

not top 5GEHC2.4%

not top 5PHIA.AS2.3%

not top 5TFX2.3%

not top 5SYK2.2%

not top 5ZBH2.2%

1.8%EXELnot top 5

1.8%AMGNnot top 5

1.8%BIIBnot top 5

1.8%GILDnot top 5

Held in common0.0%

End-of-day Nov 6, 2026 · share of each fund

XBI vs MDEV Returns, Every Period

SPDRXBI

+4.2%

5 years, per year

MDEVFirst Trust

−2.4%

5 years, per year

XBIMDEVFaded: behind in that period

4–0XBI wins

End-of-day Nov 6, 2026 · dividends in · faded = behind in that period

XBI vs MDEV

YTD

SPDRXBI

+25.0%

MDEVFirst Trust

+7.9%

+25.0%Year to date+7.9%

−14.9%Worst drop · 1Y−18.2%

30.0%Volatility · 1Y17.4%

0.4%Yield0.1%

$10.9BAssets$3.5M

3–1XBI wins

End-of-day Nov 6, 2026 · smaller drop and lower volatility win

Cost, Income and Risk

Fees: XBI, MDEV

Today

0.35%lowest, XBI

FundExpense ratioFee$10k

XBI0.35%$35

MDEV0.70%$70

End-of-day Nov 6, 2026 · fee on $10,000 a year

Yields: XBI, MDEV

0.36%highest, XBI

FundTrailing yieldYield$10k

XBI0.36%$36

MDEV0.10%$10

End-of-day Nov 6, 2026 · trailing 12-month yield

Income After Fees on $10,000

$1most kept, XBI

XBI$36 − $35 = $1

MDEV$10 − $70 = −$60

KeptFee

End-of-day Nov 6, 2026 · yield in dollars minus the fee

Overlap: XBI, MDEV

Today

0.0%most shared, XBI and MDEV

XBIMDEV

XBI—0.0%

MDEV0.0%—

End-of-day Nov 6, 2026 · share held in common · outlined: the pair in versus

Return vs Bumpiness: 2 ETFs

+40.0%XBI, at 30.0% volatility

MDEVWorst drop−18.2%17.4% vol

XBIWorst drop−14.9%30.0% vol

End-of-day Nov 6, 2026 · up and left is better

Paid More vs Made More

YTD

XBIMDEV

+25.0%Year to date+7.9%

0.4%Yield0.1%

+40.0%Past year+11.0%

0.35%Fee0.70%

4–0XBI wins

End-of-day Nov 6, 2026

Popular Pairs Near These Two

SCHD vs VIG

YTD

SchwabSCHD

+31.4%

VIGVanguard

+12.1%

+31.4%Year to date+12.1%

3.0%Yield1.5%

$120BAssets$109B

2–0SCHD wins

End-of-day Nov 6, 2026

JEPQ vs JEPI

YTD

J.P. MorganJEPQ

+3.2%

JEPIJ.P. Morgan

+5.3%

+3.2%Year to date+5.3%

12.8%Yield8.1%

$42.6BAssets$46.8B

1–1level

End-of-day Nov 6, 2026

SPYM vs SPY

YTD

SPDRSPYM

+8.8%

SPYSPDR

+8.7%

+8.8%Year to date+8.7%

1.1%Yield1.0%

$182BAssets$819B

2–0SPYM wins

End-of-day Nov 6, 2026