CANC vs VOO

ACANC

BVOO

Measures won1–4VOO wins · of 6 · 5Y

$10,000 · 5Y$17,749VOO · SPY $17,688

Lowest cost0.03%VOO · $3 on $10k

Most income1.07%VOO · $107 on $10k

Smallest drop−8.9%SPY · worst fall in 1Y

Held in common4.4%CANC and VOO

CANC

VOO

Tema Oncology ETF · $213MVanguard S&P 500 ETF · $1.00T

+27.0%3 years · per year$20,477 · $19,094+24.1%

[…]5 years · per year[…] · $17,749+12.2%

0.99%Expense ratio$99 · $3 on $10k · lower wins0.03%

0.05%12-mo yield$5 · $107 on $10k1.07%

−13.2%Worst dropSmaller wins−8.9%

23.5%VolatilityLower wins12.7%

1–4VOO wins

$10,000 · 5 yearsAll three, one scale

Shared top holdingsCANC · VOO

5.4%LLY1.4%

2.5%JNJ1.0%

4.0%ABBV0.7%

5.0%MRK0.5%

Held in common4.4%

End-of-day Nov 3, 2026 · $10,000 5 years ago, dividends reinvested · ● winner of the row · each row scaled to the bigger of the two

All Three

5Y3 funds

#
1	BVOO	Vanguard S&P 500 ETFRead Desk	0.03%	1.07%	+0.3%	+11.5%	+11.9%	+24.1%	+12.2%	−8.9%	$1.00T
2	SPY	State Street SPDR S&P 500 ETFRead Desk	0.09%	1.01%	+0.3%	+11.5%	+11.8%	+24.0%	+12.1%	−8.9%	$798.0B
3	ACANC	Tema Oncology ETFRead Desk	0.99%	0.05%	+1.0%	+21.3%	+36.0%	+27.0%	new	−13.2%	$213M

End-of-day Nov 3, 2026 · total return, dividends in · 3Y and 5Y per year · A and B = the pair in versus

All Three

5Y3 funds

#
1	BVOO	Vanguard S&P 500 ETFRead Desk	0.03%	1.07%	+0.3%	+11.5%	+11.9%	+24.1%	+12.2%	−8.9%	$1.00T
2	SPY	State Street SPDR S&P 500 ETFRead Desk	0.09%	1.01%	+0.3%	+11.5%	+11.8%	+24.0%	+12.1%	−8.9%	$798.0B
3	ACANC	Tema Oncology ETFRead Desk	0.99%	0.05%	+1.0%	+21.3%	+36.0%	+27.0%	new	−13.2%	$213M

End-of-day Nov 3, 2026 · total return, dividends in · 3Y and 5Y per year · A and B = the pair in versus

Cards for this view

CANC vs VOO

CANC

Tema Oncology

[…]

VOO

Vanguard S&P 500

$17,749

MeasureCANCVOO

Fee0.99%0.03%

Cost on $10k a year$99$3

Yield0.05%1.07%

5 years, per year[…]+12.2%

3 years, per year+27.0%+24.1%

Worst drop · 1Y−13.2%−8.9%

Volatility · 1Y23.5%12.7%

4–1measures won
VOO first

4.4%

holdings shared

Nov 3, 2026 · $10,000 five years ago, dividends reinvested

SPYM vs SPY

YTD

SPDRSPYM

+11.5%

SPYSPDR

+11.5%

+11.5%Year to date+11.5%

1.0%Yield1.0%

$185BAssets$798B

0–0level

End-of-day Nov 3, 2026

VOO vs IVV

YTD

VanguardVOO

+11.5%

IVViShares

+11.6%

+11.5%Year to date+11.6%

1.1%Yield1.1%

$1.00TAssets$872B

1–0IVV wins

End-of-day Nov 3, 2026

SCHD vs VIG

YTD

SchwabSCHD

+32.8%

VIGVanguard

+14.0%

+32.8%Year to date+14.0%

3.0%Yield1.5%

$121BAssets$109B

2–0SCHD wins

End-of-day Nov 3, 2026

Overlap: CANC, VOO, SPY

Today

95.5%most shared, VOO and SPY

CANCVOOSPY

CANC—4.4%4.8%

VOO4.4%—95.5%

SPY4.8%95.5%—

End-of-day Nov 3, 2026 · share held in common · outlined: the pair in versus

Income After Fees on $10,000

$104most kept, VOO

VOO$107 − $3 = $104

SPY$101 − $9 = $92

CANC$5 − $99 = −$94

KeptFee

End-of-day Nov 3, 2026 · yield in dollars minus the fee