CANC vs VOO

ACANC

BVOO

Measures won1–4VOO wins · of 6 · 5Y

$10,000 · 5Y$18,118IVV · VOO $18,115

Lowest cost0.03%VOO · $3 on $10k

Most income1.09%IVV · $109 on $10k

Smallest drop−8.9%SPY · worst fall in 1Y

Held in common4.4%CANC and VOO

CANC

VOO

Tema Oncology ETF · $215MVanguard S&P 500 ETF · $1.00T

+27.4%3 years · per year$20,660 · $19,172+24.2%

[…]5 years · per year[…] · $18,115+12.6%

0.99%Expense ratio$99 · $3 on $10k · lower wins0.03%

0.05%12-mo yield$5 · $105 on $10k1.05%

−13.2%Worst dropSmaller wins−8.9%

23.5%VolatilityLower wins12.8%

1–4VOO wins

$10,000 · 5 yearsAll four, one scale

Shared top holdingsCANC · VOO

5.3%LLY1.4%

2.5%JNJ1.0%

3.9%ABBV0.7%

4.8%MRK0.5%

Held in common4.4%

End-of-day Nov 4, 2026 · $10,000 5 years ago, dividends reinvested · ● winner of the row · each row scaled to the bigger of the two

All Four

5Y4 funds

#
1	IVV	iShares Core S&P 500 ETFRead Desk	0.03%	1.09%	+1.6%	+13.4%	+13.5%	+24.2%	+12.6%	−8.9%	$886.8B
2	BVOO	Vanguard S&P 500 ETFRead Desk	0.03%	1.05%	+1.6%	+13.4%	+13.5%	+24.2%	+12.6%	−8.9%	$1.00T
3	SPY	State Street SPDR S&P 500 ETFRead Desk	0.09%	0.99%	+1.7%	+13.3%	+13.4%	+24.1%	+12.6%	−8.9%	$804.8B
4	ACANC	Tema Oncology ETFRead Desk	0.99%	0.05%	+1.9%	+23.5%	+40.0%	+27.4%	new	−13.2%	$215M

End-of-day Nov 4, 2026 · total return, dividends in · 3Y and 5Y per year · A and B = the pair in versus

All Four

5Y4 funds

#
1	IVV	iShares Core S&P 500 ETFRead Desk	0.03%	1.09%	+1.6%	+13.4%	+13.5%	+24.2%	+12.6%	−8.9%	$886.8B
2	BVOO	Vanguard S&P 500 ETFRead Desk	0.03%	1.05%	+1.6%	+13.4%	+13.5%	+24.2%	+12.6%	−8.9%	$1.00T
3	SPY	State Street SPDR S&P 500 ETFRead Desk	0.09%	0.99%	+1.7%	+13.3%	+13.4%	+24.1%	+12.6%	−8.9%	$804.8B
4	ACANC	Tema Oncology ETFRead Desk	0.99%	0.05%	+1.9%	+23.5%	+40.0%	+27.4%	new	−13.2%	$215M

End-of-day Nov 4, 2026 · total return, dividends in · 3Y and 5Y per year · A and B = the pair in versus

Cards for this view

CANC vs VOO

CANC

Tema Oncology

[…]

VOO

Vanguard S&P 500

$18,115

MeasureCANCVOO

Fee0.99%0.03%

Cost on $10k a year$99$3

Yield0.05%1.05%

5 years, per year[…]+12.6%

3 years, per year+27.4%+24.2%

Worst drop · 1Y−13.2%−8.9%

Volatility · 1Y23.5%12.8%

4–1measures won
VOO first

4.4%

holdings shared

Nov 4, 2026 · $10,000 five years ago, dividends reinvested

SPYM vs SPY

YTD

SPDRSPYM

+13.4%

SPYSPDR

+13.3%

+13.4%Year to date+13.3%

1.0%Yield1.0%

$182BAssets$805B

1–0SPYM wins

End-of-day Nov 4, 2026

SCHD vs VIG

YTD

SchwabSCHD

+35.3%

VIGVanguard

+16.4%

+35.3%Year to date+16.4%

2.9%Yield1.4%

$123BAssets$109B

2–0SCHD wins

End-of-day Nov 4, 2026

JEPQ vs JEPI

YTD

J.P. MorganJEPQ

+8.5%

JEPIJ.P. Morgan

+8.8%

+8.5%Year to date+8.8%

12.2%Yield7.8%

$42.1BAssets$46.1B

1–1level

End-of-day Nov 4, 2026

Overlap: CANC, VOO, SPY, IVV

Today

99.9%most shared, SPY and IVV

CANCVOOSPYIVV

CANC—4.4%4.9%4.9%

VOO4.4%—94.5%94.5%

SPY4.9%94.5%—99.9%

IVV4.9%94.5%99.9%—

End-of-day Nov 4, 2026 · share held in common · outlined: the pair in versus

Income After Fees on $10,000

$106most kept, IVV

IVV$109 − $3 = $106

VOO$105 − $3 = $102

SPY$99 − $9 = $90

CANC$5 − $99 = −$94

KeptFee

End-of-day Nov 4, 2026 · yield in dollars minus the fee