Compare SBIO and XBI | ETF Tracker

SBIO and XBI, Ranked

Today

FundFeeYieldYTD1 year3 yrs · yr5 yrs · yrWorst dropVolatilityAssetsAvg rank

State Street SPDR S&P Biotech ETFSectors · Health care0.35%0.35%+27.2%+38.1%+34.5%+4.7%−14.9%29.1%$10.5B1.0

ALPS Medical Breakthroughs ETFSectors · Health care0.50%0.00%+6.1%+20.4%+33.9%+4.1%−29.2%32.4%$182M2.0

Rank among the two1st → 2ndFee, drop and volatility: lower ranks higherAvg rank: mean of the 8 ranks · 1 is best

End-of-day Nov 3, 2026 · returns include dividends · since: SBIO 2014 · XBI 2006

Head to Head

Swap sides Versus in desk

Head to Head

5Y

ALPS Medical Breakthroughs ETF · $182M$12,243

SBIO

XBI

State Street SPDR S&P Biotech ETF · $10.5B$12,576

$10,000 five years ago, dividends reinvested · they hold 18.7% in common

SBIOMeasureXBI

+6.1%Year to dateJan 1 → Nov 3+27.2%

+20.4%1 yearTotal return+38.1%

+33.9%3 years · per year$10,000 became $24,004 · $24,320+34.5%

+4.1%5 years · per year$10,000 became $12,243 · $12,576+4.7%

0.50%Expense ratio$50 · $35 a year on $10k · lower is better0.35%

0.00%Trailing 12-mo yield$0 · $35 a year on $10k0.35%

−29.2%Worst dropSmaller is better−14.9%

32.4%VolatilityLower is calmer29.1%

SBIOXBI Winner of the row, in its colourEach row: the bigger of the two fills its side

0–8XBI wins

End-of-day Nov 3, 2026 · returns include dividends · 3Y and 5Y figures are per-year returns

More Ways to See the Pairs

SBIO vs XBI: Top 5 Holdings

Today

SBIO

18.1%in top 5

XBI

in top 59.7%

SBIOStockXBI

4.3%ORKAnot top 5

3.8%CGONnot top 5

3.7%MANEnot top 5

3.2%TVTXnot top 5

3.2%DNTHnot top 5

not top 5MRNA2.4%

not top 5TWST2.0%

not top 5NTRA1.9%

not top 5HALO1.8%

not top 5BIIB1.7%

Held in common18.7%

End-of-day Nov 3, 2026 · share of each fund

SBIO vs XBI Returns, Every Period

5Y

ALPSSBIO

+4.1%

5 years, per year

XBISPDR

+4.7%

5 years, per year

SBIOXBIFaded: behind in that period

0–4XBI wins

End-of-day Nov 3, 2026 · dividends in · faded = behind in that period

SBIO vs XBI

YTD

ALPSSBIO

+6.1%

XBISPDR

+27.2%

+6.1%Year to date+27.2%

−29.2%Worst drop · 1Y−14.9%

32.4%Volatility · 1Y29.1%

0.0%Yield0.4%

$182MAssets$10.5B

4–0XBI wins

End-of-day Nov 3, 2026 · smaller drop and lower volatility win

Cost, Income and Risk

Fees: SBIO, XBI

Today

0.35%lowest, XBI

FundExpense ratioFee$10k

XBI0.35%$35

SBIO0.50%$50

End-of-day Nov 3, 2026 · fee on $10,000 a year

Yields: SBIO, XBI

1Y

0.35%highest, XBI

FundTrailing yieldYield$10k

XBI0.35%$35

SBIO0.00%$0

End-of-day Nov 3, 2026 · trailing 12-month yield

Income After Fees on $10,000

1Y

$0most kept, XBI

XBI$35 − $35 = $0

SBIO$0 − $50 = −$50

KeptFee

End-of-day Nov 3, 2026 · yield in dollars minus the fee

Overlap: SBIO, XBI

Today

18.7%most shared, SBIO and XBI

SBIOXBI

SBIO—18.7%

XBI18.7%—

End-of-day Nov 3, 2026 · share held in common · outlined: the pair in versus

Return vs Bumpiness: 2 ETFs

1Y

+38.1%XBI, at 29.1% volatility

XBIWorst drop−14.9%29.1% vol

SBIOWorst drop−29.2%32.4% vol

End-of-day Nov 3, 2026 · up and left is better

Paid More vs Made More

YTD

XBISBIO

+27.2%Year to date+6.1%

0.4%Yield0.0%

+38.1%Past year+20.4%

0.35%Fee0.50%

4–0XBI wins

End-of-day Nov 3, 2026

Popular Pairs Near These Two

SCHD vs VIG

YTD

SchwabSCHD

+32.8%

VIGVanguard

+14.0%

+32.8%Year to date+14.0%

3.0%Yield1.5%

$121BAssets$109B

2–0SCHD wins

End-of-day Nov 3, 2026

JEPQ vs JEPI

YTD

J.P. MorganJEPQ

+7.5%

JEPIJ.P. Morgan

+7.0%

+7.5%Year to date+7.0%

12.3%Yield8.0%

$41.8BAssets$46.0B

2–0JEPQ wins

End-of-day Nov 3, 2026

SPYM vs SPY

YTD

SPDRSPYM

+11.5%

SPYSPDR

+11.5%

+11.5%Year to date+11.5%

1.0%Yield1.0%

$185BAssets$798B

0–0level

End-of-day Nov 3, 2026