Franklin TempletonSectorsHealth Care#93 of 264 by YTD

Franklin Genomic Advancements ETFHELX

S&P 500 Compare

$42.190.0%

+$0.00 · Nov 9 close

Buy

AUM: $35M
Fee: 0.50%
Yield: 0.3%

Bumpy · 1Y: 1.8×S&P
Volume: 371
NAV: $44.03

What's insideAll 71 →

GH 8.7%NTRA 8.1%ADPT 4.9%KRYS 4.8%

52-week range9% below the high

$31.24$46.22

Returns	Today	1W	1M	3M	YTD	1Y	3Y	5Y	Max
Total return	0.0%	−3.2%	−1.1%	+1.8%	+16.2%	+21.8%	+61.8%	−21.1%	+77.4%
Peer average	+2.4%	+2.8%	+6.4%	+5.5%	+23.4%	+33.1%	+76.7%	+28.9%	—
S&P 500 · VOO	+2.3%	+0.1%	−3.3%	−2.1%	+11.3%	+13.6%	+81.6%	+75.4%	—

HELX in One Breath

HELX Among Health Care ETFs

YTD

#1IDNAiShares+67.1%$363M

#2ARKGARK+66.6%$2.2B

#3XHSSPDR+37.5%$241M

#4BBHVanEck+37.1%$524M

#5FTXHFirst Trust+35.3%$1.2B

#6BBPVirtus+30.8%$133M

#7PSCHInvesco+29.7%$181M

#8XBISPDR+28.8%$10.3B

#25HELXFranklin Templeton+16.2%$35.2M

End-of-day Nov 10, 2026 · 33 Health care ETFs by YTD

$10,000 in HELX

$10,000 in HELX became

$7,892

In the S&P 500 (VOO)

$17,543

Total return, dividends in · Nov 1, 2021 – Nov 9, 2026 · S&P 500 uses VOO

HELX’s Top Holdings

Today

GHGuardant Health8.7%NTRA8.1%ADPT4.9%KRYS4.8%LGND4.6%TWST3.5%BBIO3.3%MEDP2.9%VRTX2.9%LLY2.7%UTHR2.7%REGN2.5%TVTX2.4%VYLR2.2%CDNA2.1%TEM2.1%RGEN2.0%GRAL1.8%CRL1.8%NBIXARGX.JAZZ41 more

GHGuardant Health8.7%NTRA8.1%ADPT4.9%KRYS4.8%LGND4.6%TWST3.5%BBIO3.3%MEDP2.9%VRTX2.9%LLY2.7%UTHR2.7%51 more

BiotechnologyMedical - DiagnosticsDrug Manufacturers - GeneralMedical - Healthcare Information ServicesMedical - InstrumentsAgricultural Inputs

Franklin Templeton HELX · 63 holdings · tile size = share of the fund · as of Nov 9, 2026

What HELX Holds

Today

Biotechnology53.5%

ADPT 4.9 · KRYS 4.8 · LGND 4.6 · TWST 3.5 · BBIO 3.3 · VRTX 2.9 · UTHR 2.7

Medical - Diagnostics & Research29.5%

GH 8.7 · NTRA 8.1 · MEDP 2.9 · CDNA 2.1 · GRAL 1.8 · CRL 1.8 · IQV 1.1

Drug Manufacturers - General3.3%

LLY 2.7 · AZN.L

Medical - Healthcare Information Services3.2%

TEM 2.1 · HNGE 1.1

Medical - Instruments & Supplies2.9%

RGEN 2.0 · SRT3.DE

Agricultural Inputs2.5%

VYLR 2.2 · CTVA

Medical - Pharmaceuticals2.4%

KNSA 1.2 · RPRX 1.1 · LQDA

Franklin Templeton HELX · share of the fund by industry · as of Nov 9, 2026

Guardant’s Share of HELX

Today

8.7%

$87 of every $1,000 in HELX is Guardant

Guardant held by HELX

$3.0M

Most Guardant per dollar

HELX8.7%

LRNZ5.4%

GNOM5.0%

ARKG4.8%

Franklin Templeton HELX · each square = $10 of $1,000 · as of Nov 9, 2026

HELX’s Share of Health Care ETFs

Today

0.0%

of the $110B in 39 Health care ETFs

HELX$35.2M0.0%

XLV$49.7B45.0%

VHT$19.1B17.3%

36 others$41.6B37.7%

Health care ETF AUM · Nov 10, 2026

HELX Fee per $100 vs Peers

Today

$0.50a year
per $100

$50 a year on $10,000

XLV$0.08

VHT$0.09

XBI$0.35

IYH$0.37

IXJ$0.38

HELX$0.50

Expense ratio · Health care peers · Nov 10, 2026

Inside HELX

63 holdings · as of Nov 9, 2026

HELX

Franklin Genomic Advancements ETF

Today

Biotechnology53.5%ADPT4.9%KRYS4.8%LGND4.6%TWST3.5%BBIO3.3%VRTX2.9%UTHR2.7%REGN2.5%TVTX2.4%NBIX1.7%ARGX.BJAZZPTCT24 more holdings15.1% of the fundMedical - Diagnostics29.5%GH8.7%NTRA8.1%MEDP2.9%CDNA2.1%GRAL1.8%CRL1.8%IQVTMOA QIA.DVCYTDrug Manufacturers - General3.3%LLYMedical - Healthcare Information Services3.2%TEM2.1%HNGEMedical - Instruments2.9%RGENSRT3.DAgricultural Inputs2.5%VYLR2.2%Medical - Pharmaceuticals2.4%KNSARPRXGKOSBIOETONCDNS

Biotechnology53.5%ADPT4.9%KRYS4.8%LGND4.6%TWST3.5%BBIO3.3%VRTX2.9%32 more holdings29.5% of the fundMedical - Diagnostics29.5%GH8.7%NTRA8.1%MEDPCDNAGRALCRL6 moreDrug Manufacturers - General3.3%LLYMedical - Healthcare Information Services3.2%TEMMedical - Instruments2.9%RGENVYLRMedical - Pharmaceuticals2.4%KNSARPRXETON

#	Ticker	Company	Weight ▼
1	GH	Guardant Health	8.65%
2	NTRA	Natera	8.08%
3	ADPT	Adaptive Biotechnologies	4.92%
4	KRYS	Krystal Biotech	4.85%
5	LGND	Ligand Pharmaceuticals	4.61%
6	TWST	Twist Bioscience	3.46%
7	BBIO	Bridgebio Pharma	3.30%
8	MEDP	Medpace	2.92%
9	VRTX	Vertex Pharmaceuticals IN	2.86%
10	LLY	ELI Lilly &	2.75%

See all 71 holdings ↓

BiotechnologyMedical - DiagnosticsDrug Manufacturers - GeneralMedical - Healthcare Information ServicesMedical - InstrumentsAgricultural InputsMedical - PharmaceuticalsMedical - DevicesDrug Manufacturers - SpecialtySoftware - ApplicationOther

Franklin Templeton HELX · current holdings by weight · as of Nov 9, 2026 · each tile is one holding · top 20 = 67.7%

All HELX Holdings

71 holdings · as of Nov 9, 2026

HELX

HELX’s Holdings

Today

#
1	GHGuardant Health	Healthcare	8.65%	$865.05	19K	$2.9M
2	NTRANatera	Healthcare	8.08%	$808.01	8,775	$2.7M
3	ADPTAdaptive Biotechnologies	Healthcare	4.92%	$492.43	59K	$1.7M
4	KRYSKrystal Biotech	Healthcare	4.85%	$484.69	5,435	$1.6M
5	LGNDLigand Pharmaceuticals	Healthcare	4.61%	$461.49	5,085	$1.6M
6	TWSTTwist Bioscience	Healthcare	3.46%	$346.31	9,673	$1.2M
7	BBIOBridgebio Pharma	Healthcare	3.30%	$330.35	15K	$1.1M
8	MEDPMedpace	Healthcare	2.92%	$292.11	1,509	$986K
9	VRTXVertex Pharmaceuticals IN	Healthcare	2.86%	$286.20	1,765	$966K
10	LLYELI Lilly	Healthcare	2.75%	$274.90	685	$927K
11	UTHRUnited Therapeutics	Healthcare	2.72%	$272.19	1,634	$918K
12	REGNRegeneron Pharmaceuticals	Healthcare	2.46%	$246.33	919	$831K
13	TVTXTravere Therapeutics	Healthcare	2.38%	$237.61	16K	$802K
14	VYLRVylor	Basic Materials	2.17%	$217.31	10K	$733K
15	CDNACaredx	Healthcare	2.13%	$212.87	9,142	$718K

Franklin Templeton HELX · every reported holding · per $10,000 = dollars of each holding in a $10,000 stake · as of Nov 9, 2026

How It Compares

HELX

Franklin Genomic Advancements ETF’s Peers

YTD


XLV	SPDRRead Desk	0.08%	+23.2%	+31.2%	$49.7B
VHT	VanguardRead Desk	0.09%	+22.2%	+29.9%	$19.1B
XBI	SPDRRead Desk	0.35%	+28.8%	+44.2%	$10.3B
IYH	iSharesRead Desk	0.37%	+22.4%	+30.4%	$4.8B
IXJ	iSharesRead Desk	0.38%	+19.1%	+27.0%	$4.7B
HELX	Franklin TempletonThis fundRead Desk	0.50%	+16.2%	+21.8%	$35M

Health care peers · YTD and past-year returns · as of Nov 10, 2026 · sorted by AUM

Head to Head

Put HELX head to head with XLV →

XLV vs HELX

YTD

XLVSPDR · Health careHELXFranklin Templeton · Health care

Year to date

+23.2%

+16.2%

XLV wins+7.0 pts

Past year

+31.2%

+21.8%

XLV wins+9.4 pts

Fee

0.08%

0.50%

XLV winslower fee

Yield

1.4%

0.3%

XLV wins+1.0 pt

AUM

$49.7B

$35.2M

XLV1410.5× more

4–0XLV wins

SPDR XLV and Franklin Templeton HELX · year-to-date · as of Nov 10, 2026 · AUM not scored

HELX vs VOO

YTD

HELX · Franklin Genomic Advancements

+16.2%

VOO · S&P 500

+11.3%

Gap

4.9 pts

Franklin Templeton HELX and Vanguard VOO · YTD total return · as of Nov 10, 2026

HELX vs Its Peer Average

YTD

HELXAvsBPeer average

1D0.0%+2.4%

1M−1.1%+6.4%

3M+1.8%+5.5%

YTD+16.2%+23.4%

1Y+21.8%+33.1%

3Y+61.8%+76.7%

5Y−21.1%+28.9%

0–7Peer average wins

38 Health care peers · each row scaled to its leader

How Bumpy Is HELX?

View

HELX

How Bumpy

1.8×the S&P 500’s swings

CalmerBumpierS&P 1×HELX

Calm rank among 7 health care funds#6

Other health care funds1.2× to 2.2×

Franklin Templeton HELX · daily swings over the past year vs the S&P 500

HELX

Worst Drop

−18.0%from its Jan 22 high

Still below the high−8.3%

$10,000 at the high is now$9,170

Franklin Templeton HELX · fall from the highest close, past year

HELX

On a Bad Day

0.9×the S&P 500’s fall

HELX’s worst day: Thursday, Nov 5

HELX

−6.3%

S&P 500

−4.4%

Up days51 of every 100

S&P 500 up days52 of every 100

Franklin Templeton HELX · average move on days the S&P 500 fell

HELX

Return for the Bumps

1Y#6 of 7 health care funds

#1XLVSPDR

most for the bumps

#2VHTVanguard

#3IYHiShares

#4IXJiShares

calmest ride

#5XBISPDR

#6HELXFranklin Templeton

#7IHIiShares

lost money

Ranked by return above cash for each unit of bumpiness (Sharpe ratio) · cash = 3.8%

HELX

Cost

Today

$50a year per $10,000

XLV

VHT

XBI

$35

IYH

$37

IHI

$37

IXJ

$38

HELX

$50

Expense ratio 0.50%, taken from the fund’s value

HELX

Volatility & Beta

25.3%annual volatility

S&P 500 volatility13.7%

Downside volatility17.4%

Beta vs SPY0.98

Correlation vs SPY0.53

Beta rank, lowest first, of 7#6

Daily total returns × √252 · past 254 trading days

HELX

Max Drawdown

−18.0%peak to trough

Peak closeJan 22, 2026

Current drawdown−8.3%

Worst day−6.29% · Nov 5

Closing prices, dividends in

HELX

Up / Down Capture

92%down capture vs SPY

Down days

92%

Up days

104%

S&P 500

100%

Up ÷ down capture1.13

Up days51.2% (S&P 52.4%)

Average daily move on SPY up days and down days

HELX

Sharpe & Sortino vs Peers

Fund	Sharpe	Sortino	Volatility	Max DD	Beta	Fee / $10k
XLV	1.66	2.85	16.9%	−10.5%	0.31	$8
VHT	1.63	2.77	16.4%	−10.4%	0.39	$9
IYH	1.61	2.73	17.0%	−10.6%	0.36	$37
IXJ	1.46	2.46	16.4%	−10.8%	0.36	$38
XBI	1.40	2.12	30.1%	−14.9%	1.15	$35
HELX	0.70	1.02	25.3%	−18.0%	0.98	$50
IHI	−0.33	−0.50	22.1%	−26.1%	0.47	$37

Sharpe = (return − 3.8% cash) ÷ volatility · Sortino uses downside volatility only

HELX

Trading

Today

−4.17%below its holdings’ value

Close$42.19

NAV$44.03

Fee per $10,000$50 a year

Avg. volume 30D11K shares

Premium / discount history starts once daily NAV is saved

Close vs net asset value, Nov 9

The Details

HELX

Fund Facts

Today

2020launched Feb 25

Tracks[…]

Exchange · CUSIPCBOE · 35473P520

StructureETF

Leverage1x

Cost on $10,000$50 a year

Go deeper

Prospectus & documents Trading & liquidity Fees & costs Distributions

Franklin Templeton HELX · fund facts · as of Nov 10, 2026

HELX

Payouts by Year

$0.14per share, Dec 2025

Distribution yield0.3%

PaidOnce a year, in December

Latest ex-date · paidDec 30 · Jan 8, 2026

4 payouts added up$0.31 a share

Franklin Templeton HELX · distributions by ex-date · 2020–2025

All Fund FactsDocuments · trading · fees · every payout

Prospectus & Documents

Trading & Liquidity

Net asset value$44.03

Premium / discount[…]

Median spread · 30D[…]

Volume today371

Average volume · 30D11K

Shares outstanding[…]

Options[…]

Fees & Costs

Net expense ratio0.50%

Gross expense ratio[…]

Management fee[…]

Cost on $10,000 a year$50.00

Our risk indicator4/5

Estimated yearly cost excludes trading costs and assumes constant assets.

Distributions

Ex-date	Paid	Per share
Dec 30, 2025	Jan 8, 2026	$0.14
Dec 30, 2021	Jan 7, 2022	$0.0040
Dec 13, 2021	Dec 21, 2021	$0.11
Dec 14, 2020	Dec 23, 2020	$0.0520

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