iShares Neuroscience and Healthcare ETFIBRN

iSharesSectorsHealth Care#192 of 264 by YTD

$33.95

+2.1% last session

+5.0% YTD

Data as of 11/4/20264:00 PM ET · End-of-day

Dividend-adjusted return from the previous close · S&P 500 uses VOOIBRNS&P 500 · VOO

Returns	1D	1M	3M	YTD	1Y	3Y	5Y	MAX
Total return	+2.1%	+6.0%	−12.0%	+5.0%	+15.8%	+77.6%	—	+40.2%
Peer average	+2.7%	+8.5%	+8.9%	+24.4%	+33.4%	+84.3%	+34.0%	—
S&P 500 · VOO	+1.6%	−1.6%	0.0%	+13.4%	+13.5%	+91.7%	+81.2%	—

Key Statistics

Open all fund facts →

AUM: $7M
Expense ratio: 0.47%
Distribution yield: 0.9%
NAV: $33.22
Volume: 3K
Avg. volume 30D: 2K
High today: $33.95
Low today: $33.53
Previous close: $33.26
52-week high: $43.01
52-week low: $27.70
Our risk indicator: 4/5

IBRN in One Breath

IBRN Among Health Care ETFs

YTD

#1ARKGARK+71.5%$2.2B

#2IDNAiShares+69.3%$340M

#3XHSSPDR+40.0%$229M

#4BBHVanEck+38.2%$525M

#5FTXHFirst Trust+36.8%$1.2B

#6PSCHInvesco+31.7%$178M

#7XBISPDR+30.6%$10.5B

#8IHEiShares+29.8%$1.6B

#32IBRNiShares+5.0%$6.6M

End-of-day Nov 5, 2026 · 33 Health care ETFs by YTD

$10,000 in IBRN

$10,000 in IBRN became

$14,017

In the S&P 500 (VOO)

$20,071

Total return, dividends in · Aug 26, 2022 – Nov 4, 2026 · S&P 500 uses VOO

IBRN’s Top Holdings

Today

BIIB5.4%NBIX5.1%ALKS4.8%PTCT4.7%EWTX4.2%ARGX4.2%AXGN3.9%PRAX3.8%SRRK3.8%DNTH3.7%DYN3.6%ACAD3.5%326030.KS3.5%HLUN-B.CO3.3%XENE3.1%BHVN3.0%SRPT2.8%NEU.AX2.4%BIOA-B.ST2.1%4588.T2.0%TSHA1.6%LBRX45 more

BIIB5.4%NBIX5.1%ALKS4.8%PTCT4.7%EWTX4.2%ARGX4.2%AXGN3.9%PRAX3.8%SRRK3.8%DNTH3.7%DYN3.6%ACAD3.5%55 more

BiotechnologyDrug Manufacturers - SpecialtyMedical - DevicesDrug Manufacturers - GeneralOther

iShares IBRN · 67 holdings · tile size = share of the fund · as of Nov 4, 2026

What IBRN Holds

Today

Biotechnology62.6%

NBIX 5.1 · PTCT 4.7 · EWTX 4.2 · ARGX 4.2 · PRAX 3.8 · SRRK 3.8 · DNTH 3.7

Drug Manufacturers - Specialty & Generic8.1%

ALKS 4.8 · HLUN-B.CO 3.3 · INDV

Medical - Devices7.3%

AXGN 3.9 · IART 1.3 · CBLL 1.1 · NPCE · CLPT

Drug Manufacturers - General5.4%

BIIB 5.4

Other holdings16.6%

4588.T 2.0 · IDIA.SW 1.5 · RUBICON.NS 1.4 · MEDCL.PA 1.1 · DYVOX.ST 1.1 · ANNX 1.1 · SLDB

iShares IBRN · share of the fund by industry · as of Nov 4, 2026

Biogen’s Share of IBRN

Today

5.4%

$54 of every $1,000 in IBRN is Biogen

Biogen held by IBRN

$360K

Most Biogen per dollar

PBE5.4%

IBRN5.4%

FMKT4.6%

FTXH3.9%

iShares IBRN · each square = $10 of $1,000 · as of Nov 4, 2026

IBRN’s Share of Health Care ETFs

Today

0.0%

of the $109B in 39 Health care ETFs

IBRN$6.6M0.0%

XLV$49.1B45.0%

VHT$19.1B17.5%

36 others$40.8B37.4%

Health care ETF AUM · Nov 5, 2026

IBRN Fee per $100 vs Peers

Today

$0.47a year
per $100

$47 a year on $10,000

XLV$0.08

VHT$0.09

XBI$0.35

IYH$0.37

IXJ$0.38

IBRN$0.47

Expense ratio · Health care peers · Nov 5, 2026

Inside IBRN

67 holdings · as of Nov 4, 2026

IBRN

iShares Neuroscience and Healthcare ETF

Today

Biotechnology62.6%NBIX5.1%PTCT4.7%EWTX4.2%ARGX4.2%PRAX3.8%SRRK3.8%DNTH3.7%DYN3.6%ACAD3.5%326030.KS3.5%XENE3.1%BHVN3.0%SRPT2.8%NEU.AX2.4%13 more holdings11.1% of the fundDrug Manufacturers - Specialty8.1%ALKS4.8%Medical - Devices7.3%AXGN3.9%IARTCBLLNPCECLPTDrug Manufacturers - General5.4%BIIB5.4%Other16.6%4588.T2.0%IDIA.SANNXSLDBOVIDCAPRBWAYDSGN17 more

Biotechnology62.6%NBIX5.1%PTCT4.7%EWTX4.2%ARGX4.2%PRAX3.8%SRRK3.8%21 more holdings36.7% of the fundDrug Manufacturers - Specialty8.1%ALKS4.8%Medical - Devices7.3%AXGNCBLLBIIBOther16.6%IDIA.SANNX25 more

#	Ticker	Company	Weight ▼
1	BIIB	Biogen	5.41%
2	NBIX	Neurocrine Biosciences	5.10%
3	ALKS	Alkermes	4.77%
4	PTCT	PTC Therapeutics	4.74%
5	EWTX	Edgewise Therapeutics	4.20%
6	ARGX	Argenx SE	4.20%
7	AXGN	Axogen	3.93%
8	PRAX	Praxis Precision Medicines	3.84%
9	SRRK	Scholar Rock	3.82%
10	DNTH	Dianthus Therapeutics	3.67%

BiotechnologyDrug Manufacturers - SpecialtyMedical - DevicesDrug Manufacturers - GeneralOther

iShares IBRN · current holdings by weight · as of Nov 4, 2026 · each tile is one holding · top 20 = 73.0%

How It Compares

IBRN

iShares Neuroscience and Healthcare ETF’s Peers

YTD


XLV	SPDRRead Desk	0.08%	+24.0%	+33.5%	$49.1B
VHT	VanguardRead Desk	0.09%	+23.3%	+32.1%	$19.1B
XBI	SPDRRead Desk	0.35%	+30.6%	+45.4%	$10.5B
IYH	iSharesRead Desk	0.37%	+23.7%	+32.8%	$4.7B
IXJ	iSharesRead Desk	0.38%	+19.7%	+28.6%	$4.6B
IBRN	iSharesThis fundRead Desk	0.47%	+5.0%	+15.8%	$7M

Health care peers · YTD and past-year returns · as of Nov 5, 2026 · sorted by AUM

Head to Head

Put IBRN head to head with XLV →

XLV vs IBRN

YTD

XLVSPDR · Health careIBRNiShares · Health care

Year to date

+24.0%

+5.0%

XLV wins+19.0 pts

Past year

+33.5%

+15.8%

XLV wins+17.7 pts

Fee

0.08%

0.47%

XLV winslower fee

Yield

1.3%

0.9%

XLV wins+0.4 pts

AUM

$49.1B

$6.6M

XLV7390.0× more

4–0XLV wins

SPDR XLV and iShares IBRN · year-to-date · as of Nov 5, 2026 · AUM not scored

IBRN vs VOO

YTD

IBRN · iShares Neuroscience and Healthcare

+5.0%

VOO · S&P 500

+13.4%

Gap

8.3 pts

iShares IBRN and Vanguard VOO · YTD total return · as of Nov 5, 2026

IBRN vs Its Peer Average

YTD

IBRNAvsBPeer average

1D+2.1%+2.7%

1M+6.0%+8.5%

3M−12.0%+8.9%

YTD+5.0%+24.4%

1Y+15.8%+33.4%

3Y+77.6%+84.3%

5Y[…]+34.0%

0–6Peer average wins

38 Health care peers · each row scaled to its leader

The Details

IBRN

Risk

4/5our risk indicator

CalmerBumpier

Volatility · 1Y26.71%

Deepest drop · 1Y−26.3%

Lowest point · 5Y−19.3%

52-week range

$33.95

$27.70−21.1% from the high$43.01

iShares IBRN · past-year price moves · as of Nov 5, 2026

IBRN

Fund Facts

Today

2022launched Aug 24

Tracks[…]

Exchange · CUSIPAMEX · 46436E353

StructureETF

Leverage1x

Cost on $10,000$47 a year

Go deeper

Prospectus & documents Trading & liquidity Fees & costs Distributions

iShares IBRN · fund facts · as of Nov 5, 2026

IBRN

Payouts by Year

$0.32per share, Dec 2025

Distribution yield0.9%

PaidOnce a year

Latest ex-date · paidDec 16 · Dec 19, 2025

4 payouts added up$0.44 a share

iShares IBRN · distributions by ex-date · 2023–2025

All Fund FactsDocuments · trading · fees · every payout

Prospectus & Documents

SEC reported portfolio · 2026-07-31 ↗SEC reported portfolio · 2026-04-30 ↗SEC reported portfolio · 2026-01-31 ↗SEC reported portfolio · 2025-10-31 ↗summary prospectus · SEC 497K ↗

Trading & Liquidity

Net asset value$33.22

Premium / discount[…]

Median spread · 30D[…]

Volume today3K

Average volume · 30D2K

Shares outstanding[…]

Options[…]

Fees & Costs

Net expense ratio0.47%

Gross expense ratio[…]

Management fee[…]

Cost on $10,000 a year$47.00

Our risk indicator4/5

Estimated yearly cost excludes trading costs and assumes constant assets.

Distributions

Ex-date	Paid	Per share
Dec 16, 2025	Dec 19, 2025	$0.32
Dec 17, 2024	Dec 20, 2024	$0.10
Dec 20, 2023	Dec 27, 2023	$0.0063
Jun 7, 2023	Jun 13, 2023	$0.0082

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