iShares Neuroscience and Healthcare ETFIBRN

iSharesSectorsHealth Care#195 of 264 by YTD

$33.30

+2.4% last session

+3.0% YTD

Data as of 11/3/20264:00 PM ET · End-of-day

Dividend-adjusted return from the previous close · S&P 500 uses VOOIBRNS&P 500 · VOO

Returns	1D	1M	3M	YTD	1Y	3Y	5Y	MAX
Total return	+2.4%	+2.7%	−12.4%	+3.0%	+11.3%	+77.0%	—	+37.5%
Peer average	+0.6%	+4.0%	+6.1%	+21.0%	+29.0%	+81.2%	+28.9%	—
S&P 500 · VOO	+0.3%	−2.6%	−1.7%	+11.5%	+11.9%	+90.9%	+77.5%	—

Key Statistics

Open all fund facts →

AUM: $7M
Expense ratio: 0.47%
Distribution yield: 1.0%
NAV: $33.22
Volume: 358
Avg. volume 30D: 2K
High today: $33.30
Low today: $33.30
Previous close: $32.52
52-week high: $43.01
52-week low: $27.70
Our risk indicator: 4/5

IBRN in One Breath

IBRN Among Health Care ETFs

YTD

#1ARKGARK+70.9%$2.2B

#2IDNAiShares+62.8%$340M

#3BBHVanEck+35.0%$525M

#4FTXHFirst Trust+33.8%$1.2B

#5XHSSPDR+32.9%$229M

#6BBPVirtus+29.5%$132M

#7XBISPDR+27.2%$10.5B

#8IHEiShares+26.9%$1.6B

#32IBRNiShares+3.0%$6.6M

End-of-day Nov 4, 2026 · 33 Health care ETFs by YTD

$10,000 in IBRN

$10,000 in IBRN became

$13,749

In the S&P 500 (VOO)

$19,751

Total return, dividends in · Aug 26, 2022 – Nov 3, 2026 · S&P 500 uses VOO

IBRN’s Top Holdings

Today

BIIB5.6%ALKS4.8%NBIX4.6%EWTX4.4%PTCT4.2%ARGX4.2%AXGN4.0%PRAX3.9%SRRK3.9%DNTH3.7%ACAD3.6%326030.KS3.5%DYN3.3%HLUN-B.CO3.3%XENE3.0%BHVN3.0%SRPT2.9%NEU.AX2.4%BIOA-B.ST2.1%4588.T1.9%TSHA1.7%LBRX45 more

BIIB5.6%ALKS4.8%NBIX4.6%EWTX4.4%PTCT4.2%ARGX4.2%AXGN4.0%PRAX3.9%SRRK3.9%DNTH3.7%ACAD3.6%326030.KS3.5%55 more

BiotechnologyDrug Manufacturers - SpecialtyMedical - DevicesDrug Manufacturers - GeneralOther

iShares IBRN · 67 holdings · tile size = share of the fund · as of Nov 3, 2026

What IBRN Holds

Today

Biotechnology62.5%

NBIX 4.6 · EWTX 4.4 · PTCT 4.2 · ARGX 4.2 · PRAX 3.9 · SRRK 3.9 · DNTH 3.7

Drug Manufacturers - Specialty & Generic8.8%

ALKS 4.8 · HLUN-B.CO 3.3 · SUPN

Medical - Devices7.2%

AXGN 4.0 · IART 1.2 · CBLL 1.0 · NPCE · CLPT

Drug Manufacturers - General5.6%

BIIB 5.6

Other holdings15.9%

4588.T 1.9 · IDIA.SW 1.6 · DYVOX.ST 1.2 · MEDCL.PA 1.1 · ANNX 1.0 · SLDB · OVID

iShares IBRN · share of the fund by industry · as of Nov 3, 2026

Biogen’s Share of IBRN

Today

5.6%

$56 of every $1,000 in IBRN is Biogen

Biogen held by IBRN

$371K

Most Biogen per dollar

IBRN5.6%

PBE5.5%

FMKT4.6%

FTXH3.9%

iShares IBRN · each square = $10 of $1,000 · as of Nov 3, 2026

IBRN’s Share of Health Care ETFs

Today

0.0%

of the $109B in 39 Health care ETFs

IBRN$6.6M0.0%

XLV$49.1B45.0%

VHT$19.1B17.5%

36 others$40.8B37.4%

Health care ETF AUM · Nov 4, 2026

IBRN Fee per $100 vs Peers

Today

$0.47a year
per $100

$47 a year on $10,000

XLV$0.08

VHT$0.09

XBI$0.35

IYH$0.37

IXJ$0.38

IBRN$0.47

Expense ratio · Health care peers · Nov 4, 2026

Inside IBRN

67 holdings · as of Nov 3, 2026

IBRN

iShares Neuroscience and Healthcare ETF

Today

Biotechnology62.5%NBIX4.6%EWTX4.4%PTCT4.2%ARGX4.2%PRAX3.9%SRRK3.9%DNTH3.7%ACAD3.6%326030.KS3.5%DYN3.3%XENE3.0%BHVN3.0%SRPT2.9%NEU.AX2.4%13 more holdings11.7% of the fundDrug Manufacturers - Specialty8.8%ALKS4.8%HLUN-B.CO3.3%SUPNMedical - Devices7.2%AXGN4.0%IARTCBLLNPCECLPTDrug Manufacturers - General5.6%BIIB5.6%Other15.9%IDIA.SANNXSLDBOVIDBWAYDSGNPRTA16 more

Biotechnology62.5%NBIX4.6%EWTX4.4%PTCT4.2%ARGX4.2%PRAX3.9%SRRK3.9%21 more holdings37.3% of the fundDrug Manufacturers - Specialty8.8%ALKS4.8%HLUN-B.CO3.3%Medical - Devices7.2%AXGN4.0%IARTNPCEDrug Manufacturers - General5.6%BIIBOther15.9%IDIA.SANNXSLDB24 more

#	Ticker	Company	Weight ▼
1	BIIB	Biogen	5.58%
2	ALKS	Alkermes	4.78%
3	NBIX	Neurocrine Biosciences	4.57%
4	EWTX	Edgewise Therapeutics	4.39%
5	PTCT	PTC Therapeutics	4.22%
6	ARGX	Argenx SE	4.21%
7	AXGN	Axogen	3.97%
8	PRAX	Praxis Precision Medicines	3.95%
9	SRRK	Scholar Rock	3.86%
10	DNTH	Dianthus Therapeutics	3.70%

BiotechnologyDrug Manufacturers - SpecialtyMedical - DevicesDrug Manufacturers - GeneralOther

iShares IBRN · current holdings by weight · as of Nov 3, 2026 · each tile is one holding · top 20 = 72.5%

How It Compares

IBRN

iShares Neuroscience and Healthcare ETF’s Peers

Today


XLV	SPDRRead Desk	0.08%	−0.3%	+29.7%	$49.1B
VHT	VanguardRead Desk	0.09%	−0.1%	+28.1%	$19.1B
XBI	SPDRRead Desk	0.35%	+1.9%	+38.1%	$10.5B
IYH	iSharesRead Desk	0.37%	−0.4%	+28.6%	$4.7B
IXJ	iSharesRead Desk	0.38%	−0.5%	+24.7%	$4.6B
IBRN	iSharesThis fundRead Desk	0.47%	+2.4%	+11.3%	$7M

Health care peers · Today’s and past-year returns · as of Nov 4, 2026 · sorted by AUM

Head to Head

Put IBRN head to head with XLV →

XLV vs IBRN

YTD

XLVSPDR · Health careIBRNiShares · Health care

Year to date

+20.4%

+3.0%

XLV wins+17.3 pts

Past year

+29.7%

+11.3%

XLV wins+18.4 pts

Fee

0.08%

0.47%

XLV winslower fee

Yield

1.4%

1.0%

XLV wins+0.4 pts

AUM

$49.1B

$6.6M

XLV7390.0× more

4–0XLV wins

SPDR XLV and iShares IBRN · year-to-date · as of Nov 4, 2026 · AUM not scored

IBRN vs VOO

YTD

IBRN · iShares Neuroscience and Healthcare

+3.0%

VOO · S&P 500

+11.5%

Gap

8.5 pts

iShares IBRN and Vanguard VOO · Today total return · as of Nov 4, 2026

IBRN vs Its Peer Average

YTD

IBRNAvsBPeer average

1D+2.4%+0.6%

1M+2.7%+4.0%

3M−12.4%+6.1%

YTD+3.0%+21.0%

1Y+11.3%+29.0%

3Y+77.0%+81.2%

5Y[…]+28.9%

1–5Peer average wins

38 Health care peers · each row scaled to its leader

The Details

IBRN

Risk

4/5our risk indicator

CalmerBumpier

Volatility · 1Y26.73%

Deepest drop · 1Y−26.3%

Lowest point · 5Y−17.8%

52-week range

$33.30

$27.70−22.6% from the high$43.01

iShares IBRN · past-year price moves · as of Nov 4, 2026

IBRN

Fund Facts

Today

2022launched Aug 24

Tracks[…]

Exchange · CUSIPAMEX · 46436E353

StructureETF

Leverage1x

Cost on $10,000$47 a year

Go deeper

Prospectus & documents Trading & liquidity Fees & costs Distributions

iShares IBRN · fund facts · as of Nov 4, 2026

IBRN

Payouts by Year

$0.32per share, Dec 2025

Distribution yield1.0%

PaidOnce a year

Latest ex-date · paidDec 16 · Dec 19, 2025

4 payouts added up$0.44 a share

iShares IBRN · distributions by ex-date · 2023–2025

All Fund FactsDocuments · trading · fees · every payout

Prospectus & Documents

SEC reported portfolio · 2026-07-31 ↗SEC reported portfolio · 2026-04-30 ↗SEC reported portfolio · 2026-01-31 ↗SEC reported portfolio · 2025-10-31 ↗summary prospectus · SEC 497K ↗

Trading & Liquidity

Net asset value$33.22

Premium / discount[…]

Median spread · 30D[…]

Volume today358

Average volume · 30D2K

Shares outstanding[…]

Options[…]

Fees & Costs

Net expense ratio0.47%

Gross expense ratio[…]

Management fee[…]

Cost on $10,000 a year$47.00

Our risk indicator4/5

Estimated yearly cost excludes trading costs and assumes constant assets.

Distributions

Ex-date	Paid	Per share
Dec 16, 2025	Dec 19, 2025	$0.32
Dec 17, 2024	Dec 20, 2024	$0.10
Dec 20, 2023	Dec 27, 2023	$0.0063
Jun 7, 2023	Jun 13, 2023	$0.0082

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