Dividend-adjusted total return · S&P 500 uses VOO · Oct 6, 2026 – Nov 4, 2026LFSCS&P 500 · VOO
| Returns | 1D | 1M | 3M | YTD | 1Y | 3Y | 5Y | MAX |
|---|---|---|---|---|---|---|---|---|
| Total return | +3.3% | +8.4% | −1.3% | +24.7% | +41.4% | — | — | +82.6% |
| Peer average | +1.6% | −3.7% | +0.7% | +9.6% | +7.0% | +93.1% | +18.4% | — |
| S&P 500 · VOO | +1.6% | −1.6% | 0.0% | +13.4% | +13.5% | +91.7% | +81.2% | — |
Key Statistics
Open all fund facts →- AUM
- $121M
- Expense ratio
- 0.79%
- Distribution yield
- 0.0%
- NAV
- $43.26
- Volume
- 3K
- Avg. volume 30D
- 4K
- High today
- $45.78
- Low today
- $44.76
- Previous close
- $44.19
- 52-week high
- $48.78
- 52-week low
- $31.02
- Our risk indicator
- 4/5
LFSC in One Breath
LFSC Among Disruptive Tech ETFs
YTDEnd-of-day Nov 5, 2026 · 25 Disruptive tech ETFs by YTD
$10,000 in LFSC
5Y$10,000 in LFSC became
$18,264
In the S&P 500 (VOO)
$13,541
Total return, dividends in · Oct 30, 2024 – Nov 4, 2026 · S&P 500 uses VOO
LFSC’s Top Holdings
TodayREPLReplimune Group10.4%LIVN6.9%COGT6.0%TVTX5.6%GH5.4%BLLN4.9%CORT4.6%SYRE4.2%MANE4.0%UTHR3.9%MIRM3.5%CYTK3.2%TMDX2.8%ICUI2.7%SVRA2.6%AXSM2.6%PVLA2.2%TRVI2.2%TWST2.1%CBLL2.1%PRAX1.9%NKTR1.6%Other
REPLReplimune Group10.4%LIVN6.9%COGT6.0%TVTX5.6%GH5.4%BLLN4.9%CORT4.6%SYRE4.2%MANE4.0%UTHR3.9%MIRMCYTKOther
BiotechnologyMedical - DevicesMedical - DiagnosticsMedical - PharmaceuticalsMedical - Instruments
Emerald LFSC · 0 holdings · tile size = share of the fund · as of Nov 4, 2026
What LFSC Holds
TodayBiotechnology64.2%
REPL 10.4 · COGT 6.0 · TVTX 5.6 · SYRE 4.2 · MANE 4.0 · UTHR 3.9 · MIRM 3.5
Medical - Devices14.3%
LIVN 6.9 · TMDX 2.8 · CBLL 2.1 · GMED 1.1 · ATEC · SENS
Medical - Diagnostics & Research12.4%
GH 5.4 · BLLN 4.9 · NEO 1.2 · RDNT
Medical - Pharmaceuticals4.6%
CORT 4.6
Medical - Instruments & Supplies2.7%
ICUI 2.7
Medical - Healthcare Information Services1.4%
WAY · HNGE
Asset Management - Bonds0.5%
RBIL · OBIL
Emerald LFSC · share of the fund by industry · as of Nov 4, 2026
Replimune’s Share of LFSC
Today10.4%
$104 of every $1,000 in LFSC is Replimune
Replimune held by LFSC
$12.6M
Emerald LFSC · each square = $10 of $1,000 · as of Nov 4, 2026
LFSC’s Share of Disruptive Tech ETFs
Today0.2%
of the $50.6B in 26 Disruptive tech ETFs
$121M0.2%
$12.8B25.4%
$11.9B23.5%
$25.8B50.9%
Disruptive tech ETF AUM · Nov 5, 2026
LFSC Fee per $100 vs Peers
TodayExpense ratio · Disruptive tech peers · Nov 5, 2026
Inside LFSC
as of Nov 4, 2026LFSC
F/M Emerald Life Sciences Innovation ETF
TodayBiotechnology64.2%REPL10.4%COGT6.0%TVTX5.6%SYRE4.2%MANE4.0%UTHR3.9%MIRM3.5%CYTK3.2%SVRA2.6%AXSM2.6%PVLA2.2%TRVI2.2%TWST2.1%PRAX8 moreMedical - Devices14.3%LIVN6.9%TMDX2.8%CBLLGMEDATECSENSMedical - Diagnostics12.4%GH5.4%BLLN4.9%NEORDNTMedical - Pharmaceuticals4.6%CORT4.6%Medical - Instruments2.7%ICUI2.7%Medical - Healthcare Information Services1.4%WAYRBIL
| # | Ticker | Company | Weight ▼ |
|---|---|---|---|
| 1 | REPL | Replimune Group | 10.44% |
| 2 | LIVN | LivaNova | 6.86% |
| 3 | COGT | Cogent Biosciences | 5.96% |
| 4 | TVTX | Travere Therapeutics | 5.65% |
| 5 | GH | Guardant Health | 5.38% |
| 6 | BLLN | Billiontoone | 4.87% |
| 7 | CORT | Corcept Therapeutics | 4.61% |
| 8 | SYRE | Spyre Therapeutics | 4.17% |
| 9 | MANE | VeraDermics | 4.03% |
| 10 | UTHR | United Therapeutics | 3.94% |
BiotechnologyMedical - DevicesMedical - DiagnosticsMedical - PharmaceuticalsMedical - InstrumentsMedical - Healthcare Information ServicesAsset Management - Bonds
Emerald LFSC · current holdings by weight · as of Nov 4, 2026 · each tile is one holding · top 20 = 82.0%
How It Compares
LFSC
F/M Emerald Life Sciences Innovation ETF’s Peers
YTDDisruptive tech peers · YTD and past-year returns · as of Nov 5, 2026 · sorted by AUM
Head to Head
Put LFSC head to head with IGV →IGV vs LFSC
YTDYear to date
LFSC wins+26.7 pts
Past year
LFSC wins+51.9 pts
Fee
IGV winslower fee
Yield
Level
AUM
IGV106.1× more
2–1LFSC wins
iShares IGV and Emerald LFSC · year-to-date · as of Nov 5, 2026 · AUM not scored
Disruptive Tech vs Thematic
Average · YTDIGV
−2.0%
LFSC
+24.7%
Thematic average
+7.7%
IGV, LFSC and the average thematic ETF · YTD return · as of Nov 5, 2026
LFSC vs VOO
YTDLFSC · F/M Emerald Life Sciences Innovation
+24.7%
VOO · S&P 500
+13.4%
Gap
11.4 pts
Emerald LFSC and Vanguard VOO · YTD total return · as of Nov 5, 2026
LFSC vs Its Peer Average
YTDLFSCAvsBPeer average
1D+3.3%+1.6%
1M+8.4%−3.7%
3M−1.3%+0.7%
YTD+24.7%+9.6%
1Y+41.4%+7.0%
3Y[…]+93.1%
5Y[…]+18.4%
4–1LFSC wins
25 Disruptive tech peers · each row scaled to its leader
The Details
LFSC
Risk
1Y4/5our risk indicator
CalmerBumpier
Volatility · 1Y28.11%
Deepest drop · 1Y−17.6%
Lowest point · 5Y−18.3%
52-week range
$45.66
$31.02−6.4% from the high$48.78
Emerald LFSC · past-year price moves · as of Nov 5, 2026
LFSC
Fund Facts
Today2024launched Oct 30
Tracks[…]
Exchange · CUSIPNASDAQ · 74933W221
StructureETF
Leverage1x
Cost on $10,000$79 a year
Go deeper
Emerald LFSC · fund facts · as of Nov 5, 2026
LFSC
Payouts by Year
Today$0no payouts on record
LFSC does not pay a distribution.
Distribution yield0.0%
Paid[…]
Latest ex-date · paid[…]
12 payouts added up[…]
Emerald LFSC · distributions by ex-date
All Fund FactsDocuments · trading · fees · every payout
Prospectus & Documents
SEC reported portfolio · 2026-08-31 ↗SEC reported portfolio · 2026-05-31 ↗SEC reported portfolio · 2026-02-28 ↗SEC reported portfolio · 2025-11-30 ↗SEC reported portfolio · 2025-08-31 ↗SEC reported portfolio · 2025-05-31 ↗SEC reported portfolio · 2025-02-28 ↗SEC reported portfolio · 2024-11-30 ↗prospectus · SEC 485BPOS ↗prospectus · SEC 485APOS ↗
Trading & Liquidity
Net asset value$43.26
Premium / discount[…]
Median spread · 30D[…]
Volume today3K
Average volume · 30D4K
Shares outstanding[…]
Options[…]
Fees & Costs
Net expense ratio0.79%
Gross expense ratio[…]
Management fee[…]
Cost on $10,000 a year$79.00
Our risk indicator4/5
Estimated yearly cost excludes trading costs and assumes constant assets.
Distributions
No payouts on record: […]
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