XLV vs SBIO
YTDYear to date
XLV wins+15.1 pts
Past year
XLV wins+6.5 pts
Fee
XLV winslower fee
Yield
XLV wins+1.3 pts
AUM
XLV262.8× more
4–0XLV wins
XLV and SBIO · year-to-date · as of Nov 5, 2026 · AUM not scored
SBIO vs S&P 500
YTD$55.81 · +2.6% last sessionDividend-adjusted total return. S&P 500 uses VOO.CompareS&P 500+ Peer avg+ Add a fund
Return1D1M3MYTD ▼1Y3Y5YMAX
Total return+2.6%+2.6%−16.9%+9.0%+27.0%+140.9%+28.2%+144.0%
Peer average+2.7%+8.5%+8.9%+24.4%+33.4%+84.3%+34.0%—
S&P 500 · VOO+1.6%−1.6%0.0%+13.4%+13.5%+91.7%+81.2%+831.3%
ALPS SBIO and Vanguard VOO · total return, dividends in · as of Nov 5, 2026
SBIO’s Holdings
TodayORKAOruka Therapeutics4.4%CGON3.8%MANE3.8%TVTX3.1%DNTH3.1%DFTX3.0%EWTX2.7%RLAY2.6%XENE2.5%AMLX2.5%ACAD2.4%DYN2.3%TARS2.1%IRON2.1%DNLI2.1%IDYA2.0%VRDN1.9%MBX1.8%ZLAB1.7%NAMS1.6%CLDX1.6%81 more
Biotechnology
ALPS SBIO · 103 holdings · tile size = share of the fund · as of Nov 4, 2026
All 39 Health Care ETFs
YTD| # | Trend | |||||||
|---|---|---|---|---|---|---|---|---|
| 1 | XLV | State Street Health Care Select Sector SPDRReadDesk | 0.08% | 1.3% | +24.0% | +24.0% | $49.1B | |
| 2 | VHT | Health CareReadDesk | 0.09% | 1.3% | +23.3% | +23.3% | $19.1B | |
| 3 | XBI | State Street SPDR S&P BiotechReadDesk | 0.35% | 0.3% | +30.6% | +30.6% | $10.6B | |
| 4 | IYH | U.S. HealthcareReadDesk | 0.37% | 1.0% | +23.7% | +23.7% | $4.9B | |
| 5 | IXJ | Global HealthcareReadDesk | 0.38% | 1.2% | +19.7% | +19.7% | $4.7B | |
| 6 | IHI | U.S. Medical DevicesReadDesk | 0.37% | 0.4% | −2.7% | −2.7% | $4.1B | |
| 7 | FHLC | Fidelity MSCI Health CareReadDesk | 0.08% | 1.1% | +23.4% | +23.4% | $3.5B | |
| 8 | ARKG | ARK Genomic RevolutionReadDesk | 0.75% | — | +71.5% | +71.5% | $2.2B | |
| 9 | IHE | U.S. PharmaceuticalsReadDesk | 0.37% | 1.3% | +29.8% | +29.8% | $1.7B | |
| 10 | IHF | U.S. Healthcare ProvidersReadDesk | 0.37% | 0.9% | +27.1% | +27.1% | $1.5B | |
| 11 | PBPH | Portfolio Building Block World Pharma and BiotechReadDesk | 0.13% | 0.1% | +26.0% | +26.0% | $1.2B | |
| 12 | FTXH | First Trust Nasdaq PharmaceuticalsReadDesk | 0.60% | 0.6% | +36.8% | +36.8% | $1.2B | |
| 13 | PPH | VanEck PharmaceuticalReadDesk | 0.36% | 1.8% | +20.4% | +20.4% | $1.2B | |
| 14 | FXH | First Trust Health Care AlphaDEXReadDesk | 0.61% | 0.5% | +26.8% | +26.8% | $1.2B | |
| 15 | PJP | PharmaceuticalsReadDesk | 0.58% | 0.9% | +26.9% | +26.9% | $579M | |
| 16 | BBH | VanEck BiotechReadDesk | 0.35% | 0.4% | +38.2% | +38.2% | $538M |
1–16 of 39Page 1 of 3
Health Care · current AUM · as of Nov 5, 2026
SBIO Payouts by Year
5YLatest payout, Dec 2024
$1.17
a share · once a year
0.0% yield
0.0% yield
5 years added up
$2.62 a share
$2.62 a share
ALPS SBIO · per-share distributions by ex-date · 2017–2024
SBIO’s Peers
YTD| # | Trend | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 1 | XLV | State Street Health Care Select Sector SPDR ETFReadVersus | 0.08% | 1.3% | +3.1% | +24.0% | +33.5% | $49.1B | |
| 2 | VHT | Vanguard Health Care ETFReadVersus | 0.09% | 1.3% | +3.1% | +23.3% | +32.1% | $19.1B | |
| 3 | XBI | State Street SPDR S&P Biotech ETFReadVersus | 0.35% | 0.3% | +2.7% | +30.6% | +45.4% | $10.6B | |
| 4 | IYH | iShares U.S. Healthcare ETFReadVersus | 0.37% | 1.0% | +3.3% | +23.7% | +32.8% | $4.9B | |
| 5 | IXJ | iShares Global Healthcare ETFReadVersus | 0.38% | 1.2% | +3.2% | +19.7% | +28.6% | $4.7B | |
| 6 | SBIO | ALPS Medical Breakthroughs ETFThis fund | 0.50% | — | +2.6% | +9.0% | +27.0% | $187M |
#31 of 33 this year · #24 cheapest of 39 · sorted by assetsOpen the Sectors table →
SBIO and its peer group · total return · as of Nov 5, 2026
Cards for This View
SBIO’s Top 10 Holdings
Today31.5%of SBIO sits in these 10
ALPS SBIO · weight in the fund · as of Nov 4, 2026
SBIO’s Holdings
TodayORKAOruka Therapeutics4.4%CGON3.8%MANE3.8%TVTX3.1%DNTH3.1%DFTX3.0%EWTX2.7%RLAY2.6%XENE2.5%AMLX2.5%ACAD2.4%DYN2.3%TARS2.1%IRON2.1%DNLI2.1%IDYA2.0%VRDN1.9%MBX1.8%ZLAB1.7%NAMS1.6%CLDX1.6%81 more
Biotechnology
ALPS SBIO · 103 holdings · tile size = share of the fund · as of Nov 4, 2026
SBIO vs Peer Average
YTDSBIOAvsBPeer average
1D+2.6%+2.7%
1M+2.6%+8.5%
3M−16.9%+8.9%
YTD+9.0%+24.4%
1Y+27.0%+33.4%
3Y+140.9%+84.3%
5Y+28.2%+34.0%
1–6Peer average wins
38 Health care peers · each row scaled to its leader