Dividend-adjusted total return · S&P 500 uses VOO · Oct 27, 2023 – Nov 3, 2026XPHS&P 500 · VOO
| Returns | 1D | 1M | 3M | YTD | 1Y | 3Y | 5Y | MAX |
|---|---|---|---|---|---|---|---|---|
| Total return | +1.1% | +1.0% | −8.1% | +15.1% | +30.1% | +87.9% | +43.0% | +419.8% |
| Peer average | +0.6% | +4.0% | +6.1% | +21.0% | +29.0% | +81.2% | +28.9% | — |
| S&P 500 · VOO | +0.3% | −2.6% | −1.7% | +11.5% | +11.9% | +90.9% | +77.5% | — |
Key Statistics
Open all fund facts →- AUM
- $459M
- Expense ratio
- 0.35%
- Distribution yield
- 0.4%
- NAV
- $63.72
- Volume
- 728K
- Avg. volume 30D
- 223K
- High today
- $65.12
- Low today
- $64.03
- Previous close
- $63.61
- 52-week high
- $74.35
- 52-week low
- $47.60
- Our risk indicator
- 4/5
XPH in One Breath
XPH Among Health Care ETFs
YTDEnd-of-day Nov 4, 2026 · 33 Health care ETFs by YTD
$10,000 in XPH
5Y$10,000 in XPH became
$14,298
In the S&P 500 (VOO)
$17,749
Total return, dividends in · Oct 26, 2021 – Nov 3, 2026 · S&P 500 uses VOO
XPH’s Top Holdings
TodayMANEVeradermics2.9%XERS2.8%PCRX2.5%AMRX2.5%LLY2.4%VTRS2.3%MAZE2.3%SEPN2.2%PRGO2.2%LGND2.2%RPRX2.2%PFE2.1%ZTS2.1%ANIP2.1%JNJ2.0%INDV2.0%OGN2.0%INVA2.0%COLL2.0%PBH2.0%DFTX2.0%SUPN2.0%
MANEVeradermics2.9%XERS2.8%PCRX2.5%AMRX2.5%LLY2.4%VTRS2.3%MAZE2.3%SEPN2.2%PRGO2.2%LGND2.2%RPRX2.2%PFE2.1%
BiotechnologyDrug Manufacturers - SpecialtyDrug Manufacturers - GeneralMedical - Pharmaceuticals
SPDR XPH · 62 holdings · top 22 shown · tile size = share of the fund · as of Nov 1, 2026
What XPH Holds
TodayBiotechnology51.1%
MANE 2.9 · XERS 2.8 · MAZE 2.3 · SEPN 2.2 · LGND 2.2 · INVA 2.0 · DFTX 2.0
Drug Manufacturers - Specialty & Generic29.5%
PCRX 2.5 · AMRX 2.5 · VTRS 2.3 · PRGO 2.2 · ZTS 2.1 · ANIP 2.1 · INDV 2.0
Drug Manufacturers - General12.5%
LLY 2.4 · PFE 2.1 · JNJ 2.0 · OGN 2.0 · MRK 2.0 · BMY 1.9
Medical - Pharmaceuticals6.9%
RPRX 2.2 · PBH 2.0 · CORT 1.5 · LQDA 1.3
SPDR XPH · share of the fund by industry · as of Nov 1, 2026
Veradermics’ Share of XPH
Today2.9%
$29 of every $1,000 in XPH is Veradermics
Veradermics held by XPH
$13.1M
SPDR XPH · each square = $10 of $1,000 · as of Nov 1, 2026
XPH’s Share of Health Care ETFs
Today0.4%
of the $109B in 39 Health care ETFs
$459M0.4%
$49.1B45.0%
$19.1B17.5%
$40.4B37.0%
Health care ETF AUM · Nov 4, 2026
XPH Fee per $100 vs Peers
TodayExpense ratio · Health care peers · Nov 4, 2026
Inside XPH
62 holdings · as of Nov 1, 2026XPH
State Street SPDR S&P Pharmaceuticals ETF
TodayBiotechnology51.1%MANE2.9%XERS2.8%MAZE2.3%SEPN2.2%LGND2.2%INVA2.0%DFTXOMERHRMYEWTX1.8%TARS1.8%AMLX1.8%MBX1.7%21 more holdings22.3% of the fundDrug Manufacturers - Specialty29.5%PCRX2.5%AMRX2.5%VTRS2.3%PRGO2.2%ZTS2.1%ANIP2.1%INDVCOLLSUPN2.0%ELAN2.0%ETON1.8%AMPHHROWPAHC2 moreDrug Manufacturers - General12.5%LLY2.4%PFE2.1%JNJ2.0%OGN2.0%MRK2.0%BMY1.9%Medical - Pharmaceuticals6.9%RPRXPBHCORTLQDA
| # | Ticker | Company | Weight ▼ |
|---|---|---|---|
| 1 | MANE | Veradermics | 2.86% |
| 2 | XERS | Xeris Biopharma | 2.76% |
| 3 | PCRX | Pacira Biosciences | 2.51% |
| 4 | AMRX | Amneal Pharmaceuticals | 2.45% |
| 5 | LLY | ELI Lilly + | 2.42% |
| 6 | VTRS | Viatris | 2.31% |
| 7 | MAZE | MAZE Therapeutics | 2.29% |
| 8 | SEPN | Septerna | 2.21% |
| 9 | PRGO | Perrigo | 2.20% |
| 10 | LGND | Ligand Pharmaceuticals | 2.18% |
BiotechnologyDrug Manufacturers - SpecialtyDrug Manufacturers - GeneralMedical - Pharmaceuticals
SPDR XPH · current holdings by weight · as of Nov 1, 2026 · each tile is one holding · top 20 = 44.7%
How It Compares
XPH
State Street SPDR S&P Pharmaceuticals ETF’s Peers
YTDHealth care peers · YTD and past-year returns · as of Nov 4, 2026 · sorted by AUM
Head to Head
Put XPH head to head with XLV →XLV vs XPH
YTDYear to date
XLV wins+5.2 pts
Past year
XPH wins+0.4 pts
Fee
XLV winslower fee
Yield
XLV wins+1.0 pt
AUM
XLV107.0× more
3–1XLV wins
SPDR XLV and SPDR XPH · year-to-date · as of Nov 4, 2026 · AUM not scored
XPH vs VOO
YTDXPH · SPDR S&P Pharmaceuticals
+15.1%
VOO · S&P 500
+11.5%
Gap
3.6 pts
SPDR XPH and Vanguard VOO · YTD total return · as of Nov 4, 2026
XPH vs Its Peer Average
YTDXPHAvsBPeer average
1D+1.1%+0.6%
1M+1.0%+4.0%
3M−8.1%+6.1%
YTD+15.1%+21.0%
1Y+30.1%+29.0%
3Y+87.9%+81.2%
5Y+43.0%+28.9%
4–3XPH wins
38 Health care peers · each row scaled to its leader
The Details
XPH
Risk
1Y4/5our risk indicator
CalmerBumpier
Volatility · 1Y23.60%
Deepest drop · 1Y−16.5%
Lowest point · 5Y−23.9%
52-week range
$64.30
$47.60−13.5% from the high$74.35
SPDR XPH · past-year price moves · as of Nov 4, 2026
XPH
Fund Facts
Today2006launched Jun 19
Tracks[…]
Exchange · CUSIPAMEX · 78464A722
StructureETF
Leverage1x
Cost on $10,000$35 a year
Go deeper
SPDR XPH · fund facts · as of Nov 4, 2026
XPH
Payouts by Year
13Y$0.0416per share, Sep 2026
Distribution yield0.4%
PaidEvery quarter
Latest ex-date · paidSep 21 · Sep 23, 2026
12 payouts added up$1.48 a share
SPDR XPH · distributions by ex-date · 2014–2026
All Fund FactsDocuments · trading · fees · every payout
Prospectus & Documents
summary prospectus · SEC 497K ↗SEC reported portfolio · 2026-06-30 ↗SEC reported portfolio · 2026-03-31 ↗SEC reported portfolio · 2025-12-31 ↗SEC reported portfolio · 2025-09-30 ↗summary prospectus · SEC 497K ↗summary prospectus · SEC 497K ↗SEC reported portfolio · 2025-06-30 ↗SEC reported portfolio · 2025-03-31 ↗SEC reported portfolio · 2024-12-31 ↗SEC reported portfolio · 2024-09-30 ↗
Trading & Liquidity
Net asset value$63.72
Premium / discount[…]
Median spread · 30D[…]
Volume today728K
Average volume · 30D223K
Shares outstanding[…]
Options[…]
Fees & Costs
Net expense ratio0.35%
Gross expense ratio[…]
Management fee[…]
Cost on $10,000 a year$35.00
Our risk indicator4/5
Estimated yearly cost excludes trading costs and assumes constant assets.
Distributions
| Ex-date | Paid | Per share |
|---|---|---|
| Sep 21, 2026 | Sep 23, 2026 | $0.0416 |
| Jun 22, 2026 | Jun 24, 2026 | $0.0590 |
| Mar 23, 2026 | Mar 25, 2026 | $0.0610 |
| Dec 22, 2025 | Dec 24, 2025 | $0.11 |
| Sep 22, 2025 | Sep 24, 2025 | $0.10 |
| Jun 23, 2025 | Jun 25, 2025 | $0.0959 |
| Mar 24, 2025 | Mar 26, 2025 | $0.15 |
| Dec 23, 2024 | Dec 26, 2024 | $0.15 |
| Sep 23, 2024 | Sep 25, 2024 | $0.19 |
| Jun 24, 2024 | Jun 26, 2024 | $0.16 |
| Mar 18, 2024 | Mar 21, 2024 | $0.17 |
| Dec 18, 2023 | Dec 21, 2023 | $0.17 |
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